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FRONTLINE Plus flea and tick treatment for large dogs, 6 pipettes

FRONTLINE Plus is a liquid flea and tick spot-on treatment for large dogs, supplied as six pipettes. The listing claims monthly application and says it also targets flea eggs, with one pipette applied to the skin at the base of the neck.

At a glance

  • The manufacturer claims fleas are killed within 24 hours and ticks within 48 hours.
  • The listing says the treatment also prevents flea eggs from hatching.
  • Applied as a spot-on at the base of the neck, with one pipette per application.
  • The listing describes a four-week treatment interval and says six pipettes provide six months of protection.
Price
£28.39Save 24%

Reference price: £37.48

Price checked: 12 Nov 2026

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Often bought together

Pros and cons

Pros

  • Six pipettes correspond to six monthly applications according to the listing, making this pack suitable for a longer treatment schedule.
  • The product is described as targeting fleas, ticks and flea eggs, rather than adult fleas alone.

Technical specifications

12 specifications
Identity
BrandFRONTLINE
ModelUSP3387
Target speciesDog
Size6 Pipettes Large
Formulation
Item formLiquid
Active ingredientFipronil
Item volume16.08 Millilitres
ColourClear
Allergen informationAllergen-Free
Use and origin
Age range8 weeks
Weight listed60 Grams
Country of originFrance

What to know before buying

  • Use one pipette on the skin at the base of the neck and follow the product directions for the stated four-week interval. The listing gives an age threshold of 8 weeks but does not specify a dog-weight range for the large-dog version, so confirm that this pack suits your dog before purchase.

What’s in the box

Included
  • No Components

Who is it for?

A good fit for

  • Owners looking for a six-dose liquid spot-on flea and tick treatment for a large dog.
  • Buyers seeking a product whose listing claims action against flea eggs as well as fleas and ticks.

Less suited to

  • Owners who prefer an oral treatment or another application format.
  • Buyers who need a clearly stated dog-weight range in the listing before choosing a dose.
FRONTLINE Plus flea and tick treatment for large dogs, 6 pipettes · photo 2
Additional product photo 2

Customer reviews on Amazon

4.5 / 5 · 2,474 ratings
  • 5 stars75%75%
  • 4 stars14%14%
  • 3 stars6%6%
  • 2 stars1%1%
  • 1 star4%4%

Aggregate ratings are broadly positive, with most ratings in the five-star category, but a smaller share are low ratings. Without customer comments, the reasons for either positive or negative experiences are not available. Ratings alone cannot establish how well this spot-on treatment performs for a particular dog.

Frequently asked questions

How often does the listing say to apply FRONTLINE Plus?

It describes one pipette every four weeks. Follow the product instructions and check suitability for your dog.

How many treatments are in this pack?

The title identifies six pipettes, and the listing says the pack provides six months of protection when used at four-week intervals.

What does the listing say it treats?

It claims to kill fleas and ticks and to stop flea eggs from hatching. These are manufacturer claims, not independently verified results.

What dog age does the listing specify?

The age range is listed as 8 weeks. The listing does not provide a weight range for the large-dog version, so check the product directions before use.

FRONTLINE Plus flea and tick treatment for large dogs, 6 pipettes · photo 3
Additional product photo 3

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